Human immunodeficiency and Hodgkin lymphoma

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Human immunodeficiency and Hodgkin lymphoma.

Presentation of Hodgkin lymphoma (HL) is distinctive in the infected individual being more advanced, accompanied by B symptoms and the presence of extranodal disease particularly lymphadenopathy of the head and neck. Bone marrow involvement may be found in over 50% of cases. Virtually all co express gamma-herpesvirus. Phenotypically there is prominence of the mixed-cellularity and lymphocyte de...

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Hodgkin Lymphoma and Anaplastic Variants of Non-Hodgkin Lymphoma

  Background and Objectives: Classic Hodgkin lymphoma (CHL), anaplastic large cell lymphoma (ALCL) and some cases of diffuse large B cell lymphoma (DLBCL) have overlapping morphologic features. Since they all represent distinct clinico-pathologic entities, we explored the differential diagnostic impact of immunophenotyping to discriminate between them. Materials and Methods:...

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Outcome in patients with non-hodgkin lymphoma and with or without human immunodeficiency virus infection.

We compared the clinical characteristics and outcomes of 100 patients with human immunodeficiency virus (HIV)-associated non-Hodgkin lymphoma (NHL; HIV-NHL) treated in the highly active antiretroviral therapy era with those of 82 HIV-negative patients with aggressive NHL. The 3-year overall survival (OS) was 37% among patients with HIV-NHL and 74% among HIV-negative patients with NHL (P<.0001)....

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hodgkin lymphoma and anaplastic variants of non-hodgkin lymphoma

background and objectives: classic hodgkin lymphoma (chl), anaplastic large cell lymphoma (alcl) and some cases of diffuse large b cell lymphoma (dlbcl) have overlapping morphologic features. since they all represent distinct clinico-pathologic entities, we explored the differential diagnostic impact of immunophenotyping to discriminate between them. materials and methods: we included 61 cases ...

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Treatment of Newly Diagnosed and Relapsed Hodgkin Lymphoma in Children

Hodgkin lymphoma (HL) accounts for about 10% of all childhood cancers. Five-year survival rates with modern therapies are now approaching >90-95% as a consequence of its significant sensitivity to both chemotherapy and radiation. The current challenge is to determine how much therapy is needed to improve survival and how to adapt treatment to the patient to prevent these long term toxicities. T...

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ژورنال

عنوان ژورنال: Transfusion and Apheresis Science

سال: 2010

ISSN: 1473-0502

DOI: 10.1016/j.transci.2010.01.008